This result is being rendered in HTML for easy viewing. You may access this content as Raw JSON or Raw XML or Raw Turtle or view this content in HTML JSON or HTML XML or HTML Turtle . Response generated in 105ms.

HTTP 200 OK

Response Headers

Server: Jetty(12.0.8)
X-Powered-By: HAPI FHIR 7.1.7-SNAPSHOT/3a5ff47c58/2024-04-05 REST Server (FHIR Server; FHIR 4.0.1/R4)
Content-Type: application/x-turtle;charset=utf-8
X-Request-ID: JcSOKCy5Vn8STIop

Response Body

@prefix fhir: <;http://hl7.org/fhir/>; .
@prefix rdf:  <;http://www.w3.org/1999/02/22-rdf-syntax-ns#>; .
@prefix rdfs: <;http://www.w3.org/2000/01/rdf-schema#>; .
@prefix sct:  <;http://snomed.info/id#>; .
@prefix xsd:  <;http://www.w3.org/2001/XMLSchema#>; .
<;https://hapi.fhir.org/baseR4/Observation/1167538/_history/1>;
        rdf:type                    fhir:Observation;
        fhir:Observation.category   [ fhir:CodeableConcept.coding  [ fhir:Coding.code    [ fhir:value  "laboratory" ];
                                                                     fhir:Coding.system  [ fhir:value  "http://terminology.hl7.org/CodeSystem/observation-category"^^xsd:anyURI ];
                                                                     fhir:index          0
                                                                   ];
                                      fhir:index                   0
                                    ];
        fhir:Observation.code       [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "69548-6" ];
                                                                     fhir:Coding.display  [ fhir:value  "Genetic variant assessment" ];
                                                                     fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                     fhir:index           0
                                                                   ]
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "69551-0" ];
                                                                               fhir:Coding.display  [ fhir:value  "Genomic Alt allele [ID]" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueString
                                              [ fhir:value  "G" ];
                                      fhir:index  4
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "92822-6" ];
                                                                               fhir:Coding.display  [ fhir:value  "Genomic coord system" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueCodeableConcept
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "LA30102-0" ];
                                                                               fhir:Coding.display  [ fhir:value  "1-based character counting" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:index  5
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "69547-8" ];
                                                                               fhir:Coding.display  [ fhir:value  "Genomic Ref allele [ID]" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueString
                                              [ fhir:value  "T" ];
                                      fhir:index  3
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "81252-9" ];
                                                                               fhir:Coding.display  [ fhir:value  "Variation Code" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueCodeableConcept
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code    [ fhir:value  "653974" ];
                                                                               fhir:Coding.system  [ fhir:value  "https://www.ncbi.nlm.nih.gov/clinvar"^^xsd:anyURI ];
                                                                               fhir:index          0
                                                                             ]
                                              ];
                                      fhir:index  7
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "53034-5" ];
                                                                               fhir:Coding.display  [ fhir:value  "Allelic state" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueCodeableConcept
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "LA6706-1" ];
                                                                               fhir:Coding.display  [ fhir:value  "heterozygous" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:index  2
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "62374-4" ];
                                                                               fhir:Coding.display  [ fhir:value  "Human reference sequence assembly version" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueCodeableConcept
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "LA14029-5" ];
                                                                               fhir:Coding.display  [ fhir:value  "GRCh37" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:index  0
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "exact-start-end" ];
                                                                               fhir:Coding.display  [ fhir:value  "Variant exact start and end" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueRange
                                              [ fhir:Range.low  [ fhir:Quantity.value  [ fhir:value  "201031644"^^xsd:decimal ]
                                                                ]
                                              ];
                                      fhir:index  6
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "48013-7" ];
                                                                               fhir:Coding.display  [ fhir:value  "Genomic reference sequence ID" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueCodeableConcept
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code    [ fhir:value  "NC_000001.10" ];
                                                                               fhir:Coding.system  [ fhir:value  "http://www.ncbi.nlm.nih.gov/nuccore"^^xsd:anyURI ];
                                                                               fhir:index          0
                                                                             ]
                                              ];
                                      fhir:index  1
                                    ];
        fhir:Observation.status     [ fhir:value  "final" ];
        fhir:Observation.subject    [ fhir:Reference.reference  [ fhir:value  "Patient/1167558" ]
                                    ];
        fhir:Observation.valueCodeableConcept
                [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "LA9633-4" ];
                                                 fhir:Coding.display  [ fhir:value  "present" ];
                                                 fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                 fhir:index           0
                                               ]
                ];
        fhir:Resource.id            [ fhir:value  "1167538" ];
        fhir:Resource.meta          [ fhir:Meta.lastUpdated  [ fhir:value  "2020-05-15T19:38:49.138+00:00"^^xsd:dateTime ];
                                      fhir:Meta.profile      [ fhir:index  0;
                                                               fhir:value  "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant"
                                                             ];
                                      fhir:Meta.source       [ fhir:value  "#svOmZfeZr64OQcP8"^^xsd:anyURI ];
                                      fhir:Meta.versionId    [ fhir:value  "1" ]
                                    ] .
<;https://hapi.fhir.org/baseR4/27796cae-b762-4524-a72b-151b5e41b687>;
        rdf:type            fhir:Bundle;
        fhir:Bundle.entry   [ fhir:Bundle.entry.fullUrl   [ fhir:value  "https://hapi.fhir.org/baseR4/Observation/1167536"^^xsd:anyURI ];
                              fhir:Bundle.entry.resource  <;https://hapi.fhir.org/baseR4/Observation/1167536/_history/1>;;
                              fhir:Bundle.entry.search    [ fhir:Bundle.entry.search.mode  [ fhir:value
                                                                              "include" ]
                                                          ];
                              fhir:index                  3
                            ];
        fhir:Bundle.entry   [ fhir:Bundle.entry.fullUrl   [ fhir:value  "https://hapi.fhir.org/baseR4/Observation/2894897"^^xsd:anyURI ];
                              fhir:Bundle.entry.resource  <;https://hapi.fhir.org/baseR4/Observation/2894897/_history/1>;;
                              fhir:Bundle.entry.search    [ fhir:Bundle.entry.search.mode  [ fhir:value
                                                                              "match" ]
                                                          ];
                              fhir:index                  1
                            ];
        fhir:Bundle.entry   [ fhir:Bundle.entry.fullUrl   [ fhir:value  "https://hapi.fhir.org/baseR4/Observation/1167538"^^xsd:anyURI ];
                              fhir:Bundle.entry.resource  <;https://hapi.fhir.org/baseR4/Observation/1167538/_history/1>;;
                              fhir:Bundle.entry.search    [ fhir:Bundle.entry.search.mode  [ fhir:value
                                                                              "match" ]
                                                          ];
                              fhir:index                  0
                            ];
        fhir:Bundle.entry   [ fhir:Bundle.entry.fullUrl   [ fhir:value  "https://hapi.fhir.org/baseR4/Observation/1167537"^^xsd:anyURI ];
                              fhir:Bundle.entry.resource  <;https://hapi.fhir.org/baseR4/Observation/1167537/_history/1>;;
                              fhir:Bundle.entry.search    [ fhir:Bundle.entry.search.mode  [ fhir:value
                                                                              "include" ]
                                                          ];
                              fhir:index                  2
                            ];
        fhir:Bundle.link    [ fhir:Bundle.link.relation  [ fhir:value  "self" ];
                              fhir:Bundle.link.url       [ fhir:value  "https://hapi.fhir.org/baseR4/Observation/?_format=html%2Fturtle&_revinclude=Observation%3Aderived-from&component-code-value-concept=http%3A%2F%2Floinc.org%7C81252-9%24https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fclinvar%7C653974"^^xsd:anyURI ];
                              fhir:index                 0
                            ];
        fhir:Bundle.total   [ fhir:value  "2" ];
        fhir:Bundle.type    [ fhir:value  "searchset" ];
        fhir:Resource.id    [ fhir:value  "27796cae-b762-4524-a72b-151b5e41b687" ];
        fhir:Resource.meta  [ fhir:Meta.lastUpdated  [ fhir:value  "2024-05-07T21:13:28.854+00:00"^^xsd:dateTime ]
                            ];
        fhir:nodeRole       fhir:treeRoot .
<;https://hapi.fhir.org/baseR4/Observation/1167536/_history/1>;
        rdf:type                       fhir:Observation;
        fhir:DomainResource.extension  [ fhir:Extension.url  [ fhir:value  "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/RelatedArtifact"^^xsd:anyURI ];
                                         fhir:Extension.valueRelatedArtifact
                                                 [ fhir:RelatedArtifact.type  [ fhir:value  "citation" ];
                                                   fhir:RelatedArtifact.url   [ fhir:value  "https://www.ncbi.nlm.nih.gov/medgen/?term=CACNA1S[gene]" ]
                                                 ];
                                         fhir:index          0
                                       ];
        fhir:DomainResource.extension  [ fhir:Extension.url  [ fhir:value  "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/RelatedArtifact"^^xsd:anyURI ];
                                         fhir:Extension.valueRelatedArtifact
                                                 [ fhir:RelatedArtifact.type  [ fhir:value  "derived-from" ];
                                                   fhir:RelatedArtifact.url   [ fhir:value  "https://www.ncbi.nlm.nih.gov/clinvar/variation/653974" ]
                                                 ];
                                         fhir:index          1
                                       ];
        fhir:Observation.code          [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "diagnostic-implication" ];
                                                                        fhir:Coding.display  [ fhir:value  "Diagnostic Implication" ];
                                                                        fhir:Coding.system   [ fhir:value  "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes"^^xsd:anyURI ];
                                                                        fhir:index           0
                                                                      ]
                                       ];
        fhir:Observation.component     [ fhir:Observation.component.code
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "93044-6" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Level of Evidence" ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:Observation.component.valueCodeableConcept
                                                 [ fhir:CodeableConcept.text  [ fhir:value  "criteria provided, single submitter" ]
                                                 ];
                                         fhir:index  0
                                       ];
        fhir:Observation.component     [ fhir:Observation.component.code
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "53037-8" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Clinical Significance" ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:Observation.component.valueCodeableConcept
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "LA26332-9" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Likely pathogenic" ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:index  1
                                       ];
        fhir:Observation.component     [ fhir:Observation.component.code
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "81259-4" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Associated Phenotype" ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:Observation.component.valueCodeableConcept
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "145600" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Malignant hyperthermia " ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://omim.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:index  2
                                       ];
        fhir:Observation.component     [ fhir:Observation.component.code
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "79742-3" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Mode of Inheritance" ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:Observation.component.valueCodeableConcept
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "LA24640-7" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Autosomal dominant" ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:index  3
                                       ];
        fhir:Observation.derivedFrom   [ fhir:Reference.reference  [ fhir:value  "Observation/1167538" ];
                                         fhir:index                0
                                       ];
        fhir:Observation.method        [ fhir:CodeableConcept.text  [ fhir:value  "ACMG screening prototype app querying https://api-gacs.elimuinformatics.com/gacs/variants/ and https://www.ncbi.nlm.nih.gov/clinvar/docs/acmg/ for Connectathon 24" ]
                                       ];
        fhir:Observation.status        [ fhir:value
                          "final" ];
        fhir:Observation.subject       [ fhir:Reference.reference  [ fhir:value  "Patient/1167558" ]
                                       ];
        fhir:Resource.id               [ fhir:value
                          "1167536" ];
        fhir:Resource.meta             [ fhir:Meta.lastUpdated  [ fhir:value  "2020-05-15T19:38:49.138+00:00"^^xsd:dateTime ];
                                         fhir:Meta.source       [ fhir:value  "#svOmZfeZr64OQcP8"^^xsd:anyURI ];
                                         fhir:Meta.versionId    [ fhir:value  "1" ]
                                       ] .
<;https://hapi.fhir.org/baseR4/Observation/2894897/_history/1>;
        rdf:type                    fhir:Observation;
        fhir:Observation.category   [ fhir:CodeableConcept.coding  [ fhir:Coding.code    [ fhir:value  "laboratory" ];
                                                                     fhir:Coding.system  [ fhir:value  "http://terminology.hl7.org/CodeSystem/observation-category"^^xsd:anyURI ];
                                                                     fhir:index          0
                                                                   ];
                                      fhir:index                   0
                                    ];
        fhir:Observation.code       [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "69548-6" ];
                                                                     fhir:Coding.display  [ fhir:value  "Genetic variant assessment" ];
                                                                     fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                     fhir:index           0
                                                                   ]
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "exact-start-end" ];
                                                                               fhir:Coding.display  [ fhir:value  "Variant exact start and end" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueRange
                                              [ fhir:Range.low  [ fhir:Quantity.value  [ fhir:value  "201031644"^^xsd:decimal ]
                                                                ]
                                              ];
                                      fhir:index  6
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "69551-0" ];
                                                                               fhir:Coding.display  [ fhir:value  "Genomic Alt allele [ID]" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueString
                                              [ fhir:value  "G" ];
                                      fhir:index  4
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "92822-6" ];
                                                                               fhir:Coding.display  [ fhir:value  "Genomic coord system" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueCodeableConcept
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "LA30102-0" ];
                                                                               fhir:Coding.display  [ fhir:value  "1-based character counting" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:index  5
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "53034-5" ];
                                                                               fhir:Coding.display  [ fhir:value  "Allelic state" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueCodeableConcept
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "LA6706-1" ];
                                                                               fhir:Coding.display  [ fhir:value  "heterozygous" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:index  2
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "48013-7" ];
                                                                               fhir:Coding.display  [ fhir:value  "Genomic reference sequence ID" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueCodeableConcept
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code    [ fhir:value  "NC_000001.10" ];
                                                                               fhir:Coding.system  [ fhir:value  "http://www.ncbi.nlm.nih.gov/nuccore"^^xsd:anyURI ];
                                                                               fhir:index          0
                                                                             ]
                                              ];
                                      fhir:index  1
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "81252-9" ];
                                                                               fhir:Coding.display  [ fhir:value  "Variation Code" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueCodeableConcept
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code    [ fhir:value  "653974" ];
                                                                               fhir:Coding.system  [ fhir:value  "https://www.ncbi.nlm.nih.gov/clinvar"^^xsd:anyURI ];
                                                                               fhir:index          0
                                                                             ]
                                              ];
                                      fhir:index  7
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "62374-4" ];
                                                                               fhir:Coding.display  [ fhir:value  "Human reference sequence assembly version" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueCodeableConcept
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "LA14029-5" ];
                                                                               fhir:Coding.display  [ fhir:value  "GRCh37" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:index  0
                                    ];
        fhir:Observation.component  [ fhir:Observation.component.code
                                              [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "69547-8" ];
                                                                               fhir:Coding.display  [ fhir:value  "Genomic Ref allele [ID]" ];
                                                                               fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                               fhir:index           0
                                                                             ]
                                              ];
                                      fhir:Observation.component.valueString
                                              [ fhir:value  "T" ];
                                      fhir:index  3
                                    ];
        fhir:Observation.status     [ fhir:value  "final" ];
        fhir:Observation.subject    [ fhir:Reference.reference  [ fhir:value  "Patient/1167558" ]
                                    ];
        fhir:Observation.valueCodeableConcept
                [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "LA9633-4" ];
                                                 fhir:Coding.display  [ fhir:value  "present" ];
                                                 fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                 fhir:index           0
                                               ]
                ];
        fhir:Resource.id            [ fhir:value  "2894897" ];
        fhir:Resource.meta          [ fhir:Meta.lastUpdated  [ fhir:value  "2022-04-14T16:50:53.073+00:00"^^xsd:dateTime ];
                                      fhir:Meta.profile      [ fhir:index  0;
                                                               fhir:value  "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant"
                                                             ];
                                      fhir:Meta.source       [ fhir:value  "#FasLkbolkaHU1ilw"^^xsd:anyURI ];
                                      fhir:Meta.versionId    [ fhir:value  "1" ]
                                    ] .
<;https://hapi.fhir.org/baseR4/Observation/1167537/_history/1>;
        rdf:type                       fhir:Observation;
        fhir:DomainResource.extension  [ fhir:Extension.url  [ fhir:value  "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/RelatedArtifact"^^xsd:anyURI ];
                                         fhir:Extension.valueRelatedArtifact
                                                 [ fhir:RelatedArtifact.type  [ fhir:value  "derived-from" ];
                                                   fhir:RelatedArtifact.url   [ fhir:value  "https://cpicpgx.org/guidelines/" ]
                                                 ];
                                         fhir:index          1
                                       ];
        fhir:DomainResource.extension  [ fhir:Extension.url  [ fhir:value  "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/RelatedArtifact"^^xsd:anyURI ];
                                         fhir:Extension.valueRelatedArtifact
                                                 [ fhir:RelatedArtifact.type  [ fhir:value  "citation" ];
                                                   fhir:RelatedArtifact.url   [ fhir:value  "https://cpicpgx.org/guidelines/cpic-guideline-for-ryr1-and-cacna1s/" ]
                                                 ];
                                         fhir:index          0
                                       ];
        fhir:Observation.code          [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "therapeutic-implication" ];
                                                                        fhir:Coding.display  [ fhir:value  "Therapeutic Implication" ];
                                                                        fhir:Coding.system   [ fhir:value  "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes"^^xsd:anyURI ];
                                                                        fhir:index           0
                                                                      ]
                                       ];
        fhir:Observation.component     [ fhir:Observation.component.code
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "51963-7" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Medication assessed" ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:Observation.component.valueCodeableConcept
                                                 [ fhir:CodeableConcept.text  [ fhir:value  "HALOGENATED VOLATILE ANESTHETICS" ]
                                                 ];
                                         fhir:index  2
                                       ];
        fhir:Observation.component     [ fhir:Observation.component.code
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "93044-6" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Level of Evidence" ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:Observation.component.valueCodeableConcept
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "1A" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Level 1A High" ];
                                                                                  fhir:Coding.system   [ fhir:value  "https://www.pharmgkb.org/page/clinAnnLevels"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:index  0
                                       ];
        fhir:Observation.component     [ fhir:Observation.component.code
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "81259-4" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Associated Phenotype" ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:Observation.component.valueCodeableConcept
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "145600" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Malignant hyperthermia " ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://omim.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:index  1
                                       ];
        fhir:Observation.component     [ fhir:Observation.component.code
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "83009-1" ];
                                                                                  fhir:Coding.display  [ fhir:value  "Medication High Risk" ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:Observation.component.valueCodeableConcept
                                                 [ fhir:CodeableConcept.coding  [ fhir:Coding.code     [ fhir:value  "LA19541-4" ];
                                                                                  fhir:Coding.display  [ fhir:value  "High risk" ];
                                                                                  fhir:Coding.system   [ fhir:value  "http://loinc.org"^^xsd:anyURI ];
                                                                                  fhir:index           0
                                                                                ]
                                                 ];
                                         fhir:index  3
                                       ];
        fhir:Observation.derivedFrom   [ fhir:Reference.reference  [ fhir:value  "Observation/1167538" ];
                                         fhir:index                0
                                       ];
        fhir:Observation.method        [ fhir:CodeableConcept.text  [ fhir:value  "CPIC screening prototype app querying https://api-gacs.elimuinformatics.com/gacs/variants/ and CPIC guidelines for Connectathon 24" ]
                                       ];
        fhir:Observation.status        [ fhir:value
                          "final" ];
        fhir:Observation.subject       [ fhir:Reference.reference  [ fhir:value  "Patient/1167558" ]
                                       ];
        fhir:Resource.id               [ fhir:value
                          "1167537" ];
        fhir:Resource.meta             [ fhir:Meta.lastUpdated  [ fhir:value  "2020-05-15T19:38:49.138+00:00"^^xsd:dateTime ];
                                         fhir:Meta.source       [ fhir:value  "#svOmZfeZr64OQcP8"^^xsd:anyURI ];
                                         fhir:Meta.versionId    [ fhir:value  "1" ]
                                       ] .
Wrote 47.2 KB (214.3 KB total including HTML) in approximately 3ms